First infusion day is a huge emotional milestone. It can feel scary, surreal, and empowering all at once.
This page is peer support, not medical advice. It is built to help you feel less anxious and more prepared for the flow of the day.
First Chemo Infusion
What first infusion day looks like, plus what to expect after.
What to Expect
Most infusion visits include check-in, labs if needed, nurse assessment, pre-meds, then treatment itself. Timing can vary a lot, first days are often longer.
You will likely meet several team members, and your will monitor you closely during treatment.
Prepare Before You Go+
- Bring water, snacks, chargers, and a comfort item like a sweater or blanket.
- Wear layers, infusion rooms can feel cold.
- Bring your medication list, including anti-nausea meds.
- Plan for a quieter evening after treatment.
- Arrange help with transport or home tasks if possible.
Questions to Ask+
- What side effects are common in the first 24 to 72 hours?
- What side effects may arise during the of treatment over the next 1 to 2 weeks?
- Which symptoms are urgent and require same-day call?
- How should I use my anti-nausea meds, scheduled or ?
- Who do I call after hours if symptoms escalate?
- When is my next visit and what should I expect then?
Make Sure You Know Before You Leave+
- Your take-home medication plan and timing.
- Clear red-flag symptom list with call instructions.
- Hydration and nutrition guidance for the next day or two.
- Your next lab or infusion date.
- How to message or call the clinic with questions.
What to Do Right After+
Prioritize hydration, rest, and simple food if tolerated. Keep a short symptom log with time, symptom, and what helped.
Do not try to be heroic through severe symptoms. Calling early is not overreacting, it is part of safe treatment.
What Happens Next+
You and your team will learn from this first and adjust support meds or timing . That is normal and expected.
By cycle two or three, many people feel less fear because the process is more familiar and personalized.
Try not to feel embarrassed or shy about bringing up strange side effects to your doctor at your next follow-up visit. Some side effects can feel very personal, but it is in your best interest to be clear and upfront with your medical team so they can best assist you and help you to minimize the effects you may be experiencing.